CD117 (c-KIT) overexpression in patients with extensive-stage small-cell lung carcinoma.

@article{Potti2003CD117O,
  title={CD117 (c-KIT) overexpression in patients with extensive-stage small-cell lung carcinoma.},
  author={Anil Potti and Nauman Moazzam and Kannan Ramar and David Hanekom and Steven Kargas and Michael Koch},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2003},
  volume={14 6},
  pages={894-7}
}
BACKGROUND The aim of this study was to determine the incidence and role of CD117 (c-KIT) overexpression as a predictive/prognostic marker in extensive-stage small-cell lung carcinoma (ESSCLC). We performed a retrospective study on subjects with a biopsy-proven diagnosis of ESSCLC. PATIENTS AND METHODS A chart review for demographic and clinical data was performed on patients with ESSCLC diagnosed between 1991 and 2001. CD117 overexpression was evaluated using immunohistochemistry (A4052… CONTINUE READING

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