CD10 as a novel marker of therapeutic resistance and cancer stem cells in head and neck squamous cell carcinoma

@inproceedings{Fukusumi2014CD10AA,
  title={CD10 as a novel marker of therapeutic resistance and cancer stem cells in head and neck squamous cell carcinoma},
  author={Takahito Fukusumi and Hiroshi Ishii and Masamitsu Konno and Taku Yasui and Susumu Nakahara and Yasuhiro Takenaka and Yumi Yamamoto and Shimpei Nishikawa and Yoshihiro Kano and Hirohisa Ogawa and Shinichiro Hasegawa and Atsushi Hamabe and Naotsugu Haraguchi and Yuichiro Doki and Miwa Mori and Hidenori Inohara},
  booktitle={British Journal of Cancer},
  year={2014}
}
Background:Cancer stem cells (CSCs) are responsible for treatment failure. However, their identification and roles in resistance are not well established in head and neck squamous cell carcinoma (HNSCC).Methods:Three HNSCC cell lines (FaDu, Detroit562 and BICR6) were treated with cisplatin or radiation. Cell surface antigens were analysed by LyoPlate, a novel cell surface antigen array. The expression levels of antigens highly expressed after treatments were further compared between cisplatin… CONTINUE READING
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