CD 1a and S100 antigen expression in skin Langerhans cells in patients with breast cancer

  title={CD 1a and S100 antigen expression in skin Langerhans cells in patients with breast cancer},
  author={AlanJ. Wilson and P. H. Maddox and David Jenkins},
  journal={The Journal of Pathology},
Langerhans cells (LCs) are dendritic, antigen‐presenting cells found in the epidermis. This study investigates the effect of early breast cancer on the expression of CD1a and S100 antigens by these cells. LCs were counted and expressed as cells/mm of epithelial basement membrane on biopsies from the skin overlying the tumour and from biopsies distant from the tumour. A control study was performed on normal breast skin, not adjacent to a lesion, from women with benign breast disease. 
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