CCSP G38A polymorphism environment interactions regulate CCSP levels differentially in COPD.

Abstract

Impaired airway homeostasis in chronic obstructive pulmonary disease (COPD) could be partly related to club cell secretory protein (CCSP) deficiency. We hypothesize that CCSP G38A polymorphism is involved and aim to examine the influence of the CCSP G38A polymorphism on CCSP transcription levels and its regulatory mechanisms. CCSP genotype and CCSP levels… (More)
DOI: 10.1152/ajplung.00280.2016

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