CCR9-CCL25 interaction suppresses apoptosis of lung cancer cells by activating the PI3K/Akt pathway.

Abstract

CC chemokine receptor-9 (CCR9) is highly expressed in non-small cell lung cancer (NSCLC) tissues and cell lines. However, the biological functions and the signals elicited by the interaction between CCR9 and its natural ligand CCL25 in NSCLC are unknown. Here, we selectively depleted CCR9 and inhibited CCR9-CCL25 interaction in NSCLC cells using small… (More)
DOI: 10.1007/s12032-015-0531-0

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@article{Li2015CCR9CCL25IS, title={CCR9-CCL25 interaction suppresses apoptosis of lung cancer cells by activating the PI3K/Akt pathway.}, author={Baijun Li and Zhiwei Wang and Yonglong Zhong and J. Lan and Xiangwei Li and Hui Lin}, journal={Medical oncology}, year={2015}, volume={32 3}, pages={66} }