CCR5 chemokine receptor variant in HIV-1 mother-to-child transmission and disease progression in children. French Pediatric HIV Infection Study Group.

@article{Misrahi1998CCR5CR,
  title={CCR5 chemokine receptor variant in HIV-1 mother-to-child transmission and disease progression in children. French Pediatric HIV Infection Study Group.},
  author={Micheline Misrahi and Jean Paul Teglas and Nicole N'go and Marianne Burgard and Marie Jeanne Mayaux and Christine Rouzioux and Jean François Delfraissy and St{\'e}phane Blanche},
  journal={JAMA},
  year={1998},
  volume={279 4},
  pages={277-80}
}
CONTEXT Studies suggest that adults with the CCR5delta32 deletion are less likely to become infected with the human immunodeficiency virus (HIV) and to develop HIV-related disease progression, but the effect of the mutation in children is not known. OBJECTIVE To study the effect of the CCR5 chemokine receptor mutant allele on mother-to-child transmission of HIV type 1 (HIV-1) and subsequent disease progression in infected children. DESIGN Multicenter, prospective study of infants born to… CONTINUE READING
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