CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context.

@article{Draper1994CCR4IA,
  title={CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context.},
  author={Michael P. Draper and Huiqing Liu and A H Nelsbach and Stephen P. Mosley and Clyde L Denis},
  journal={Molecular and cellular biology},
  year={1994},
  volume={14 7},
  pages={4522-31}
}
The yeast CCR4 protein is required for the expression of a number of genes involved in nonfermentative growth, including glucose-repressible ADH2, and is the only known suppressor of mutations in the SPT6 and SPT10 genes, two genes which are believed to be involved in chromatin maintenance. We show here that although CCR4 did not bind DNA under the conditions tested, it was able to activate transcription when fused to a heterologous DNA-binding domain. The transcriptional activation ability of… CONTINUE READING
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