CCN3 secretion is regulated by palmitoylation via ZDHHC22.

@article{Kim2018CCN3SI,
  title={CCN3 secretion is regulated by palmitoylation via ZDHHC22.},
  author={Yujin Kim and Hayoung Yang and Jeong-Ki Min and Young-Jun Park and Seung Hun Jeong and S U Jang and Sungbo Shim},
  journal={Biochemical and biophysical research communications},
  year={2018},
  volume={495 4},
  pages={2573-2578}
}
Normal extracellular secretion of nephroblastoma overexpressed (NOV, also known as CCN3) is important for the adhesion, migration, and differentiation of cells. In previous studies, we have shown that the intracellular accumulation of CCN3 inhibits the growth of prominent neurons. Increased intracellular CCN3 can be induced through various processes, such as transcription, detoxification, and posttranslational modification. In general, posttranslational modifications are very important for… CONTINUE READING
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