CCN2 protein is an announcing marker for cardiac remodeling following STZ-induced moderate hyperglycemia in mice.

@article{Kaminski2009CCN2PI,
  title={CCN2 protein is an announcing marker for cardiac remodeling following STZ-induced moderate hyperglycemia in mice.},
  author={Karol Adam Kaminski and Barbara Szepietowska and Tomasz Andrzej Bonda and Marcin Kożuch and Joanna Mencel and Andrzej Małkowski and Krzysztof Ludwik Sobolewski and Oksana M. Kovalchuk and Lech Chyczewski and Małgorzata Szelachowska and Maria G{\'o}rska and Włodzimierz Jerzy Musiał and Maria Małgorzata Winnicka},
  journal={Pharmacological reports : PR},
  year={2009},
  volume={61 3},
  pages={
          496-503
        }
}
Diabetes causes changes in the myocardium, which are often called diabetic cardiomyopathy. This condition has been extensively investigated in animal models with high glucose levels. Nevertheless, it has not been investigated whether moderate hyperglycemia, in the absence of other features of metabolic syndrome, may also cause similar changes in the heart. The aim of the study was to assess changes in the myocardium in an animal model of mild type 1 diabetes. Moderate hyperglycemia was induced… CONTINUE READING
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