CCL2 as a trigger of manifestations of compensatory anti-inflammatory response syndrome in mice with severe systemic inflammatory response syndrome.

@article{Takahashi2006CCL2AA,
  title={CCL2 as a trigger of manifestations of compensatory anti-inflammatory response syndrome in mice with severe systemic inflammatory response syndrome.},
  author={Hitoshi Takahashi and Yasuhiro Tsuda and Makiko Kobayashi and David N . Herndon and Fujio Suzuki},
  journal={Journal of leukocyte biology},
  year={2006},
  volume={79 4},
  pages={789-96}
}
Patients with compensatory anti-inflammatory response syndrome (CARS) are at a higher risk for infection with various opportunistic pathogens. CARS develops commonly in association with the manifestation of systemic inflammatory response syndrome (SIRS). In the present study, the role of SIRS-associated soluble factors on the CARS development was examined in mice with pancreatitis, a carrier of typical SIRS. Following the production of SIRS-related cytokines [tumor necrosis factor alpha and… CONTINUE READING

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