CCL18/DC-CK-1/PARC up-regulation in hypersensitivity pneumonitis.

@article{Pardo2001CCL18DCCK1PARCUI,
  title={CCL18/DC-CK-1/PARC up-regulation in hypersensitivity pneumonitis.},
  author={Annie Pardo and Karen M.J. Smith and John Abrams and Robert V. Coffman and Ma.Emilia Bustos and Terrill K. Mcclanahan and J. T. Grein and Erin Emma Murphy and Albert Zlotnik and Mois{\'e}s Selman},
  journal={Journal of leukocyte biology},
  year={2001},
  volume={70 4},
  pages={
          610-6
        }
}
Hypersensitivity pneumonitis (HP) is a lung inflammatory disorder characterized by accumulation of T lymphocytes. However, the mechanisms implicated in this process remain undefined. We examined the expression of dendritic cell (DC)-derived CC chemokine 1 (CK1)/CCL18, a chemokine putatively involved in naive T cell recruitment, in lungs from 10 patients with HP, 9 patients with idiopathic pulmonary fibrosis (IPF), and 20 healthy lungs. CCL18 was measured by real-time quantitative PCR and… CONTINUE READING

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