CCK-58 is the only detectable endocrine form of cholecystokinin in rat.

@article{Reeve2003CCK58IT,
  title={CCK-58 is the only detectable endocrine form of cholecystokinin in rat.},
  author={Joseph R. Reeve and Gary M. Green and P. E. D. Chew and Viktor Ernst Eysselein and David A. Keire},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2003},
  volume={285 2},
  pages={G255-65}
}
CCK-58 differs from CCK-8 in patterns of expression of pancreatic secretion of fluid and amylase and gallbladder contraction. These differences have physiological relevance only if CCK-58 release is stimulated by nutrients entering the intestine and if CCK-58 circulates in sizeable amounts. In this study, we report that when radiolabeled CCK-58 is added to rat blood and plasma is formed, there is extensive loss and degradation of the radioactive peptide. Therefore, a new method was developed to… CONTINUE READING

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References

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Accelerated in vitro degradation of G264 ENDOCRINE FORMS OF CCK AJP-Gastrointest Liver Physiol

  • CJ Springer, GA Eberlein, VE Eysselein, M Schaeffer, H Goebell, J. Calam
  • Clin Chim Acta 198:
  • 2003
1 Excerpt

CCK-58 and pancreatitis: enhanced pancreatic fluid secretion by CCK-58 minimizes pancreatic injury in response to supramaximal stimulation (Abstract). Pancreas

  • M Yamamoto, Reeve JR, GM Green
  • 2001
1 Excerpt

CCK - 58 and pancreatitis : enhanced pancreatic fluid secretion by CCK58 minimizes pancreatic injury in response to supramaximal stimulation ( Abstract )

  • M Yamamoto, Reeve, GM Green
  • Digestion
  • 1999

CCK extended structure markedly influences pancreatic secretion in conscious rats (Abstract)

  • M Yamamoto, Reeve, JR, GM Green
  • Digestion
  • 1999
3 Excerpts

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