CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms.

@article{Kraaijeveld2007CCCL,
  title={CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms.},
  author={Adriaan O. Kraaijeveld and Saskia C. A. de Jager and W de Jager and Berent Prakken and Shaun R McColl and Inge Haspels and Hein Putter and Theo J. C. van Berkel and Lex M Nagelkerken and Jan Wouter Jukema and Erik A. L. Biessen},
  journal={Circulation},
  year={2007},
  volume={116 17},
  pages={1931-41}
}
BACKGROUND Chemokines play an important role in atherogenesis and in ischemic injury and repair; however, prospective data on individual chemokines in unstable angina pectoris (UAP) are scarce. Therefore, we assessed chemokine patterns in a prospective cohort of patients with UAP. METHODS AND RESULTS Plasma samples of 54 patients with Braunwald class IIIB UAP were examined at baseline for 11 chemokines and 5 inflammatory mediators via multiplex analysis. Levels of CC chemokine ligand (CCL)-5… CONTINUE READING