CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis.

Abstract

CCL2 is a chemokine known to recruit monocytes and macrophages to sites of inflammation. A growing body of research suggests CCL2 is progressively overexpressed in tumor beds and may play a role in the clinical progression of solid tumors. Cancer cells derived from several solid tumor types demonstrate functional receptors for CCL2, suggesting this… (More)
DOI: 10.1016/j.cytogfr.2009.11.009

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