CBNAAT : a Novel Diagnostic Tool For Rapid And Specific Detection Of Mycobacterium Tuberculosis In Pulmonary Samples
@inproceedings{Sowjanya2015CBNAATA, title={CBNAAT : a Novel Diagnostic Tool For Rapid And Specific Detection Of Mycobacterium Tuberculosis In Pulmonary Samples}, author={D. S. Sowjanya and Ganeswar Behera and V. V. Ramana Reddy and J. V. Praveen}, year={2015} }
Mycobacterium tuberculosis remains to be one of the most significant causes of death from an infectious agent. Rapid diagnosis of tuberculosis and detection of Rifampicin (RIF) resistance are essential for effective disease management. CBNAAT (Cartridge Based Nucliec Acid Amplification Test) also known as Gene Xpert MTB/RIF assay is a novel integrated diagnostic device for the diagnosis of tuberculosis and rapid detection of RIF resistance in clinical specimens. We determined the performance of…
15 Citations
Cepheid GeneXpert Mycobacterium tuberculosis/Rifampicin assay for the rapid detection of Mycobacterium tuberculosis and identification of Rifampicin resistance
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- 2018
The MTB/RIF test is a simple and rapid method, and staff with adequate training can perform this test with minimal laboratory setup, and offers high potential for the diagnosis of TB and RIF resistance.
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CBNAAT helps in increased case detection in lesser time to diagnose pulmonary tuberculosis as compared to conventional sputum microscopy and detects the rifampicin resistance with high specificity to start early treatment.
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The GeneXpert polymerase chain reaction test (known in India as CBNAAT) and is capable of diagnosing TB and rifampicin resistance within 2 h) is a promising tool and should be used as a near-point-of-care test.
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CBNAAT detects pulmonary TB with greater efficacy than sputum microscopy also helping in early diagnosis in less than 2 hours and can be used for screening for MDR-TB so that early therapy can be started thus decreasing the incidence of M DR-TB.
Roleof Cartridge-Based Nucleic Acid Amplification Test (Cbnaat) For Early Diagnosis of Tuberculosis: A Retrospective Study
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CBNAAT is an important diagnostic modality especially in sputum negative patients for early diagnosis and treatment in lesser time as compared to conventional sputUM microscopy and it detects the rifampicin resistance with high specificity to start early treatment.
Role of cartridge -based nucleic acid amplification test (CBNAAT) for early diagnosis of pulmonary tuberculosis in HIV
- Medicine, BiologyIP Indian Journal of Immunology and Respiratory Medicine
- 2019
CBNAAT is a rapid, reliable tool with least bio-safety concern and requires minimally trained staff, is best alternative to conventional methods of tubercular diagnosis and detects rifampicin resistance simultaneously within 2 hours.
Role of Cartridge Based Nucleic Acid Amplification Testing in Diagnosis of Extrapulmonary Tuberculosis- Experience from a Teaching Institution in Eastern India
- Medicine
- 2021
CBNAAT adds significantly to the diagnostic yield of EPTB in comparison to conventional methods, but its sensitivity varies in different forms of extrapulmonary tuberculosis.
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- Medicine, Biology
- 2016
The overall prevalence of rifampicin resistance is 22.64% among previously treated pulmonary tuberculosis, and the failure case is significantly associated with rifampsic in resistance.
PREVALENCE OF POSITIVITY OF CBNAAT IN PULMONARY TUBERCULOSIS
- MedicineInternational Journal of Medical and Biomedical Studies
- 2022
CBNAAT detects pulmonary TB with greater efficacy than sputum microscopy also helping in early diagnosis in less than 2 hours and can be used for screening for MDR-TB so that early therapy can be started thus decreasing the incidence of M DR-TB.
Is Cartridge Based Nucleic Acid Amplification Test (CBNAAT) Better Than Conventional Tests in Diagnosing Childhood Tuberculosis? Evidence from a Tertiary Care Hospital in Eastern India
- Medicine, Biology
- 2019
CBNAAT assay is highly sensitive and specific to detect tuberculosis rapidly comparing to the traditional tests with rifampicin resistance associated with mutation of rpoB gene in a single test, and helps in avoiding injudicious use of anti-tubercular drugs.
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