CBA/J mice infected with Trypanosoma cruzi: an experimental model for inflammatory myopathies.

@article{Andersson2003CBAJMI,
  title={CBA/J mice infected with Trypanosoma cruzi: an experimental model for inflammatory myopathies.},
  author={John Andersson and Pernilla Englund and Dan Sunnemark and Anders J. Dahlstedt and H{\aa}kan Westerblad and Inger Nennesmo and Anders Orn and Ingrid E Lundberg},
  journal={Muscle & nerve},
  year={2003},
  volume={27 4},
  pages={442-8}
}
Idiopathic inflammatory myopathies are inflammatory disorders of unknown origin, characterized by muscle weakness. The aim of our study was to establish and characterize an animal model for chronic inflammatory myopathy which would permit investigations of the role of T-cells in chronic myositis as well as of the mechanisms for muscle weakness in chronic inflammatory muscle disorders. CBA/J mice were infected with the protozoan parasite Trypanosoma cruzi. Immunohistochemistry was used to… CONTINUE READING