CB2 receptors in reproduction.

  title={CB2 receptors in reproduction.},
  author={Mauro Maccarrone},
  journal={British journal of pharmacology},
  volume={153 2},
Cannabinoids have been always identified as harmful drugs because of their negative effects on male and female reproduction. The discovery of the 'endocannabinoid system (ECS)', composed of bioactive lipids (endocannabinoids), their receptors and their metabolic enzymes, and the generation of mouse models missing cannabinoid receptors or other elements of the ECS, has enabled a wealth of information on the significance of endocannabinoid signalling in multiple reproductive events: Sertoli cell… CONTINUE READING
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