CB1 cannabinoid receptor signalling in Parkinson's disease.

  title={CB1 cannabinoid receptor signalling in Parkinson's disease.},
  author={Jonathan Michael Brotchie},
  journal={Current opinion in pharmacology},
  volume={3 1},
Signalling at CB(1) cannabinoid receptors plays a key role in the control of movement in health and disease. In recent years, an increased understanding of the physiological role of transmission at CB(1) receptors throughout the basal ganglia circuitry has led to the identification of novel therapeutic approaches to both the symptoms of Parkinson's disease and the side effects of current anti-parkinsonian therapies, especially L(3,4) dihydroxyphenylalamine (levodopa)-induced dyskinesia. Thus… CONTINUE READING