CB1 Cannabinoid Receptor Expression in the Striatum: Association with Corticostriatal Circuits and Developmental Regulation

@inproceedings{Waes2012CB1CR,
  title={CB1 Cannabinoid Receptor Expression in the Striatum: Association with Corticostriatal Circuits and Developmental Regulation},
  author={Vincent Van Waes and Joel A. Beverley and Homayoun Siman and Kuei Yuan Tseng and Heinz Steiner},
  booktitle={Front. Pharmacol.},
  year={2012}
}
Corticostriatal circuits mediate various aspects of goal-directed behavior and are critically important for basal ganglia-related disorders. Activity in these circuits is regulated by the endocannabinoid system via stimulation of CB1 cannabinoid receptors. CB1 receptors are highly expressed in projection neurons and select interneurons of the striatum, but expression levels vary considerably between different striatal regions (functional domains). We investigated CB1 receptor expression within… CONTINUE READING