CATs and HATs: the SLC7 family of amino acid transporters

@article{Verrey2004CATsAH,
  title={CATs and HATs: the SLC7 family of amino acid transporters},
  author={Fran�ois Verrey and Ellen I. Closs and Carsten A. Wagner and M. Palac{\'i}n and H. Endou and Y. Kanai},
  journal={Pfl{\"u}gers Archiv},
  year={2004},
  volume={447},
  pages={532-542}
}
  • Fran�ois Verrey, Ellen I. Closs, +3 authors Y. Kanai
  • Published 2004
  • Chemistry, Medicine
  • Pflügers Archiv
  • The SLC7 family is divided into two subgroups, the cationic amino acid transporters (the CAT family, SLC7A1–4) and the glycoprotein-associated amino acid transporters (the gpaAT family, SLC7A5–11), also called light chains or catalytic chains of the hetero(di)meric amino acid transporters (HAT). The associated glycoproteins (heavy chains) 4F2hc (CD98) or rBAT (D2, NBAT) form the SLC3 family. Members of the CAT family transport essentially cationic amino acids by facilitated diffusion with… CONTINUE READING
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