CAST: an iterative algorithm for the complexity analysis of sequence tracts

@article{Promponas2000CASTAI,
  title={CAST: an iterative algorithm for the complexity analysis of sequence tracts},
  author={Vasilis J. Promponas and Anton J. Enright and Sophia Tsoka and David P. Kreil and Christophe Leroy and Stavros J. Hamodrakas and Chris Sander and Christos A. Ouzounis},
  journal={Bioinformatics},
  year={2000},
  volume={16 10},
  pages={915-22}
}
MOTIVATION Sensitive detection and masking of low-complexity regions in protein sequences. Filtered sequences can be used in sequence comparison without the risk of matching compositionally biased regions. The main advantage of the method over similar approaches is the selective masking of single residue types without affecting other, possibly important, regions. RESULTS A novel algorithm for low-complexity region detection and selective masking. The algorithm is based on multiple-pass Smith… CONTINUE READING
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