CARCINOMA OF THE ISLANDS OF LANGERHANS WITH HYPOGLYCEMIA AND METASTASIS TO THE LIVER

@article{Flinn1941CARCINOMAOT,
  title={CARCINOMA OF THE ISLANDS OF LANGERHANS WITH HYPOGLYCEMIA AND METASTASIS TO THE LIVER},
  author={L. B. Flinn and G. A. Beatty and M. Ginsberg and F. A. Hemsath},
  journal={JAMA},
  year={1941},
  volume={117},
  pages={283-285}
}
After the discovery of insulin in 1922 the signs and symptoms of acute hypoglycemia became well known. These, in cases of mild involvement, were weakness, perspiration and anxiety and in severe instances more serious mental changes, convulsions, coma and death. The mental changes have received more attention lately, especially in association with insulin therapy in some of the psychoses. Apparently the hypoglycemic effect on nervous tissue may reach a point at times which is irreversible… Expand
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