CAPTOPRIL IN THE TREATMENT OF CLINICAL HYPERTENSION AND CARDIAC FAILURE
@article{Atkinson1979CAPTOPRILIT, title={CAPTOPRIL IN THE TREATMENT OF CLINICAL HYPERTENSION AND CARDIAC FAILURE}, author={Anthony B. Atkinson and J. Ian S. Robertson}, journal={The Lancet}, year={1979}, volume={314}, pages={836-839} }
370 Citations
Inflammatory nephrocutaneous diseases including associated cutaneous and renal manifestations and referral considerations Disease Cutaneous findings Renal findings
- Medicine
- 2016
This review discusses important nephrocutaneous disease associations and recommendations for the appropriate urgency of referral to nephrology colleagues for diagnosis, surveillance, and early management of potential renal sequelae.
Analytical strategies for the characterization, identification, and quantification of peptides and proteins of interest in the prevention and understanding of hypertension
- Philosophy
- 2014
La hipertension constituye un serio problema de salud y esta considerada como una de las causas de las enfermedades cardiovasculares y renales. A pesar de la prevalencia de la hipertension, la mitad…
Seasonal variation in nitrogenous components and bioactivity of protein hydrolysates from Porphyra dioica
- BiologyJournal of Applied Phycology
- 2017
The results demonstrate the potential of P. dioica hydrolysates as health-enhancing food components or natural food preservatives due to their enzyme inhibitory and antioxidant activities.
Angiotensin-I-converting enzyme and prolyl endopeptidase inhibitory peptides from marine processing by-products
- Chemistry
- 2011
Combination Therapy with Paricalcitol and Enalapril Ameliorates Cardiac Oxidative Injury in Uremic Rats
- Biology, MedicineAmerican Journal of Nephrology
- 2008
Treatment with enalapril, paricalcitol or the combination of the two protected uremic rats from cardiac oxidative stress by inhibiting enzyme activity.
Pharmacological potential of seaweed-associated heterotrophic bacterium Bacillus atrophaeus
- BiologyArchives of Microbiology
- 2022
The heterotrophic B. atrophaeus SHB2097 could be used to develop potential therapeutic and biomedical agents and the significance of nuclear magnetic resonance-centered analyses of distinguishing signals in the organic extract and correlating those with bioactive potential was accentuated.
Hempseed (Cannabis sativa) protein hydrolysates: A valuable source of bioactive peptides with pleiotropic health-promoting effects
- Trends in Food Science & Technology
- 2022
An exploration of ACE inhibitory peptides derived from gastrointestinal protease hydrolysate of milk using a modified bioassay-guided fractionation approach coupled with in silico analysis
- MedicineJournal of Dairy Science
- 2022
An improved bioassay-guided fractionation was performed to effectively screen angiotensin-I converting enzyme inhibitory (ACEI) peptides from milk protein hydrolysate. The aqueous normal phase liquid…
Isolation, identification, and molecular docking analysis of novel ACE inhibitory peptides from Spirulina platensis
- Biology, ChemistryEuropean Food Research and Technology
- 2022
Novel insights are provided for the development of ACE inhibitors and the high-value utilization of Spirulina platensis for blood pressure regulation and bioactive peptide production.
Antimicrobial Activity and Toxicity of Analogs of Wasp Venom EMP Peptides. Potential Influence of Oxidized Methionine
- BiologyAntibiotics
- 2021
Only EMP-AF-OR showed concentration-dependent growth inhibition against all bacterial species tested, and the hemolytic activity of the analogs were moderated though reports of the natural peptides, especially EMP-af-OR, already showed low toxicity against erythrocytes.
References
SHOWING 1-10 OF 60 REFERENCES
Mechanism of blood pressure reduction by teprotide (SQ 20881) in rats.
- Biology, MedicineKidney international
- 1978
Teprotide did not appear to exert its hypotensive effect by any mechanism other than inhibition of the renin-angiotensin system and given at a maximally effective dose to the rat, it produced no greater vasodepressor effect than did saralasin.
Increased glomerular filtration rate after converting-enzyme inhibition in essential hypertension.
- Medicine, BiologyThe New England journal of medicine
- 1979
Observations suggest that a functional element, perhaps involving angiotensin-mediated renal vasoconstriction, frequently has a role in the reduction in glomerular filtration rate that occurs in essential hypertension, which may improve renal excretory function as it controls hypertension.
Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents.
- Chemistry, BiologyScience
- 1977
A hypothetical model of the active site of angiotensin-converting enzyme, based on known chemical and kinetic properties of the enzyme, has enabled a new class of potent and specific inhibitors, carboxyalkanoyl and mercaptoalkanoysl derivatives of proline, to be designed.
INNAPPROPRIATE RENIN SECRETION UNMASKED BY CAPTOPRIL (SQ 14 225) IN HYPERTENSION OF CHRONIC RENAL FAILURE
- MedicineThe Lancet
- 1978
A slowly developing pressor response to small concentrations of angiotensin. Its bearing on the pathogenesis of chronic renal hypertension.
- MedicineLancet
- 1963
SQ 14,225 (D-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme.
- ChemistryThe Journal of pharmacology and experimental therapeutics
- 1978
Captopril (SQ 14,225) (D-3-mercapto-2-methylpropranoyl-L-proline): a novel orally active inhibitor of angiotensin-converting enzyme and antihypertensive agent.
- Medicine, BiologyProgress in cardiovascular diseases
- 1978