CAPTOPRIL IN THE TREATMENT OF CLINICAL HYPERTENSION AND CARDIAC FAILURE

@article{Atkinson1979CAPTOPRILIT,
  title={CAPTOPRIL IN THE TREATMENT OF CLINICAL HYPERTENSION AND CARDIAC FAILURE},
  author={Anthony B. Atkinson and J. Ian S. Robertson},
  journal={The Lancet},
  year={1979},
  volume={314},
  pages={836-839}
}
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370 Citations
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370 Citations

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References

SHOWING 1-10 OF 60 REFERENCES

Book Review: Mild Hypertension: Natural History and Management

NEPHROTIC SYNDROME IN PATIENT ON

Mechanism of blood pressure reduction by teprotide (SQ 20881) in rats.

Teprotide did not appear to exert its hypotensive effect by any mechanism other than inhibition of the renin-angiotensin system and given at a maximally effective dose to the rat, it produced no greater vasodepressor effect than did saralasin.

Increased glomerular filtration rate after converting-enzyme inhibition in essential hypertension.

Observations suggest that a functional element, perhaps involving angiotensin-mediated renal vasoconstriction, frequently has a role in the reduction in glomerular filtration rate that occurs in essential hypertension, which may improve renal excretory function as it controls hypertension.

Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents.

A hypothetical model of the active site of angiotensin-converting enzyme, based on known chemical and kinetic properties of the enzyme, has enabled a new class of potent and specific inhibitors, carboxyalkanoyl and mercaptoalkanoysl derivatives of proline, to be designed.

Reversible renal failure during treatment with captopril.

INNAPPROPRIATE RENIN SECRETION UNMASKED BY CAPTOPRIL (SQ 14 225) IN HYPERTENSION OF CHRONIC RENAL FAILURE

A slowly developing pressor response to small concentrations of angiotensin. Its bearing on the pathogenesis of chronic renal hypertension.

SQ 14,225 (D-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme.

Captopril (SQ 14,225) (D-3-mercapto-2-methylpropranoyl-L-proline): a novel orally active inhibitor of angiotensin-converting enzyme and antihypertensive agent.

...