CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles.

@article{Liu2008CAPSFF,
  title={CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles.},
  author={Yuanyuan Liu and Claudia Schirra and David R. Stevens and Ulf Matti and Dina Speidel and Detlef Hof and Dieter Bruns and Nils Brose and Jens Rettig},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2008},
  volume={28 21},
  pages={5594-601}
}
Calcium-activator protein for secretion (CAPS) is a cytosolic protein that associates with large dense-core vesicles and is involved in their secretion. Mammals express two CAPS isoforms, which share a similar domain structure including a Munc13 homology domain that is believed to be involved in the priming of secretory vesicles. A variety of studies designed to perturb CAPS function indicate that CAPS is involved in the secretion of large dense-core vesicles, but where in the secretory pathway… CONTINUE READING
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