CAMs and Igs: Cell Adhesion and the Evolutionary Origins of Immunity

@article{Edelman1987CAMsAI,
  title={CAMs and Igs: Cell Adhesion and the Evolutionary Origins of Immunity},
  author={Gerald M. Edelman},
  journal={Immunological Reviews},
  year={1987},
  volume={100}
}
  • G. Edelman
  • Published 1 December 1987
  • Biology
  • Immunological Reviews
The lymphoid system and cells of immunity are as morphologically well defined as those of any complex organ but in addition they show dynamic long-range interactions between the fluid tissues (lymphocytes, monocytes, etc.) and the solid, vascular and generative tissues and organs which they comprise. Given the observation that CAMs are present in epithelial components of lymphoid organs, it appears that, in their ontogeny, the organs of immunity will share a common principle of morphoregulation… 

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  • Biology
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  • Biology, Medicine
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Thyroxine-dependent modulations of the expression of the neural cell adhesion molecule N-CAM during Xenopus laevis metamorphosis.

This work has studied by immunohistofluorescence and immunoblots the patterns of expression of N-CAM at different stages of Xenopus laevis metamorphosis, thought to play a central role in the control of morphogenetic processes.
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