CAMTA1 is a novel tumour suppressor regulated by miR-9/9* in glioblastoma stem cells.

@article{Schraivogel2011CAMTA1IA,
  title={CAMTA1 is a novel tumour suppressor regulated by miR-9/9* in glioblastoma stem cells.},
  author={Daniel Schraivogel and Lasse Weinmann and D Beier and Ghazaleh Tabatabai and Alexander Eichner and Jia Yun Zhu and Martina Anton and Michael Sixt and Michael Weller and Christoph Patrick Beier and Gunter Meister},
  journal={The EMBO journal},
  year={2011},
  volume={30 20},
  pages={4309-22}
}
Cancer stem cells or cancer initiating cells are believed to contribute to cancer recurrence after therapy. MicroRNAs (miRNAs) are short RNA molecules with fundamental roles in gene regulation. The role of miRNAs in cancer stem cells is only poorly understood. Here, we report miRNA expression profiles of glioblastoma stem cell-containing CD133(+) cell populations. We find that miR-9, miR-9(*) (referred to as miR-9/9(*)), miR-17 and miR-106b are highly abundant in CD133(+) cells. Furthermore… CONTINUE READING