CAG repeat polymorphism within the KCNN3 gene is a significant contributor to susceptibility to anorexia nervosa: a case-control study of female patients and several ethnic groups in the Israeli Jewish population.

@article{KoronyoHamaoui2004CAGRP,
  title={CAG repeat polymorphism within the KCNN3 gene is a significant contributor to susceptibility to anorexia nervosa: a case-control study of female patients and several ethnic groups in the Israeli Jewish population.},
  author={Maya Koronyo-Hamaoui and Eva Gak and D{\'a}niel Stein and A. W. Frisch and Yardena Danziger and Shani Leor and Elena Michaelovsky and Neil Laufer and Cynthia Carel and Silvana Fennig and Marc Mimouni and Alan Apter and Boleslav Goldman and Gad Barkai and Abraham Weizman},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2004},
  volume={131B 1},
  pages={76-80}
}
The human small-conductance Ca(2+)-activated potassium channel gene KCNN3 has been involved in mechanisms underlying neuronal function and plasticity. A multiallelic CAG repeat polymorphism within the KCNN3 has been associated with schizophrenia and bipolar disorder. We have previously reported in a family-based study that longer CAG repeats are preferentially transmitted to patients with anorexia nervosa (AN). The present study extends the analysis of KCNN3 allele distribution to a larger… CONTINUE READING

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