CAG/CTG and CGG/GCC repeats in human brain reference cDNAs: outcome in searching for new dynamic mutations.

@article{Albanse1998CAGCTGAC,
  title={CAG/CTG and CGG/GCC repeats in human brain reference cDNAs: outcome in searching for new dynamic mutations.},
  author={V Alban{\`e}se and S{\'e}bastien Holbert and C Saada and Sebastian Meier-Ewert and A S Lebre and Sylvain Morini{\`e}re and L. Bougueleret and I M Le Gall and Jean Weissenbach and Greg Lennon and Hans Lehrach and Daniel Cohen and Howard M. Cann and Cinzia Neri},
  journal={Genomics},
  year={1998},
  volume={47 3},
  pages={414-8}
}
CAG and CGG expansion is associated with 10 inherited neurological diseases and is thought to be involved in other human genetic diseases. To identify new candidate genes, we have undertaken a large-scale screening project for CAG/CTG ([CAG]n) and CGG/GCC ([CGG]n) repeats in human brain reference cDNAs. Here, we present the final classification for 597 cDNAs selected by CAG and CGG hybridization from two libraries (100,128 clones) and the updated characterization of [CAG]n- and [CGG]n-positive… CONTINUE READING