CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer.

@article{Strooper2014CADM1MA,
  title={CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer.},
  author={Lise M A De Strooper and Marjolein van Zummeren and Renske D. M. Steenbergen and Maaike C G Bleeker and Albertus Theodorus Hesselink and G Bea A Wisman and Peter J. F. Snijders and Dani{\"e}lle A M Heideman and Chris J L M Meijer},
  journal={Journal of clinical pathology},
  year={2014},
  volume={67 12},
  pages={1067-71}
}
AIMS Gene promoter hypermethylation is recognised as an essential early step in carcinogenesis, indicating important application areas for DNA methylation analysis in early cancer detection. The current study was set out to assess the performance of CADM1, MAL and miR124-2 methylation analysis in cervical scrapes for detection of cervical and endometrial cancer. METHODS A series of cervical scrapes of women with cervical (n=79) or endometrial (n=21) cancer, cervical intraepithelial neoplasia… CONTINUE READING