CADASIL: hereditary arteriopathy leading to multiple brain infarcts and dementia.

@article{Viitanen2000CADASILHA,
  title={CADASIL: hereditary arteriopathy leading to multiple brain infarcts and dementia.},
  author={Matti H. Viitanen and Hannu Kalimo},
  journal={Annals of the New York Academy of Sciences},
  year={2000},
  volume={903},
  pages={273-84}
}
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) often begins with migraine with aura. Recurrent strokes usually appear between 30 and 50 years of age. The arteriopathy develops slowly, resulting in destruction of smooth muscle cells and thickening and fibrosis of the walls of small and medium-sized penetrating arteries with consequent narrowing of the lumen. This impairs cerebral blood flow, visible in PET, and produces characteristic white… CONTINUE READING