CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity

@article{Ou2015CACNA1CRG,
  title={CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity},
  author={Xiao Ou and David E. Crane and Bradley J MacIntosh and Lionel Trevor Young and Benjamin I Goldstein},
  journal={Neuroscience & Biobehavioral Reviews},
  year={2015},
  volume={55},
  pages={198-210}
}
Recently, multiple genome-wide association studies have identified a genetic polymorphism (CACNA1C rs1006737) that appears to confer susceptibility for BD. This article aims to summarize the existing literature regarding the impact of rs1006737 on functional and structural neuroimaging intermediate phenotypes. Twenty eight articles, representing 2486 healthy participants, 369 patients with BD and 104 healthy first-degree relatives of patients with BD, are incorporated. Multiple studies have… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 84 REFERENCES

Effects of a CACNA1C genotype on attention networks in healthy individuals.

  • Psychological medicine
  • 2011
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

CACNA1C (rs1006737) is associated with schizophrenia

  • Molecular Psychiatry
  • 2010
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL