C60-Fullerenes: detection of intracellular photoluminescence and lack of cytotoxic effects

@article{Levi2006C60FullerenesDO,
  title={C60-Fullerenes: detection of intracellular photoluminescence and lack of cytotoxic effects},
  author={Nicole H. Levi and Roy R. Hantgan and Mark O. Lively and D. L. Carroll and Gaddamanugu L Prasad},
  journal={Journal of Nanobiotechnology},
  year={2006},
  volume={4},
  pages={14 - 14}
}
We have developed a new method of application of C60 to cultured cells that does not require water-solubilization techniques. Normal and malignant cells take-up C60 and the inherent photoluminescence of C60 is detected within multiple cell lines. Treatment of cells with up to 200 μg/ml (200 ppm) of C60 does not alter morphology, cytoskeletal organization, cell cycle dynamics nor does it inhibit cell proliferation. Our work shows that pristine C60 is non-toxic to the cells, and suggests that… CONTINUE READING
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Nano-C60 cytotoxicity is due to lipid peroxidation.

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  • 2005
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