C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice.


BACKGROUND Receptor binding of complement C5a leads to proinflammatory activation of many cell types, but the role of receptor-mediated action during arterial remodeling after injury has not been studied. In the present study, we examined the contribution of the C5a receptor (C5aR) to neointima formation in apolipoprotein E-deficient mice employing a C5aR… (More)
DOI: 10.1161/CIRCULATIONAHA.110.954370


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