C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

@inproceedings{Yuan2012C5aAI,
  title={C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis},
  author={Jun Yuan and Shen-ju Gou and Jing Huang and Jian Hao and Min Chen and Ming-Hui Zhao},
  booktitle={Arthritis research & therapy},
  year={2012}
}
INTRODUCTION The complement system is crucial for the development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). In particular, C5a plays a central role. In this study, plasma and urinary levels of C5a as well as renal C5a receptors (CD88 and C5L2) expression were investigated in patients with AAV. METHODS Twenty-four patients with AAV in the active phase, 19 patients with AAV in the remission phase, and 20 patients with lupus nephritis (LN) were included. Plasma… CONTINUE READING
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