C57BL/6J mice show greater amphetamine-induced locomotor activation and dopamine efflux in the striatum than 129S2/SvHsd mice.

@article{Chen2007C57BL6JMS,
  title={C57BL/6J mice show greater amphetamine-induced locomotor activation and dopamine efflux in the striatum than 129S2/SvHsd mice.},
  author={Rong Chen and Minjia Zhang and Soo Yun Park and Margaret E. Gnegy},
  journal={Pharmacology, biochemistry, and behavior},
  year={2007},
  volume={87 1},
  pages={158-63}
}
Inbred strains of mice have served as valuable models for studying genetic susceptibility to drug addiction, an alternative to genetically modified mouse models. This is the first study comparing amphetamine (AMPH) effects on locomotor stimulation and dopamine efflux between two inbred strains of mice C57BL/6J and 129S2/SvHsd, frequently used as background strains for production of genetically engineered mice. There were no significant differences in basal locomotor activity and basal dopamine… CONTINUE READING
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