C4-dicarboxylate transport in Bacillus subtilis studied with 3-fluoro-L-erythro-malate as a substrate.

@article{Willecke1974C4dicarboxylateTI,
  title={C4-dicarboxylate transport in Bacillus subtilis studied with 3-fluoro-L-erythro-malate as a substrate.},
  author={Klaus Willecke and Rita Lange},
  journal={Journal of bacteriology},
  year={1974},
  volume={117 2},
  pages={373-8}
}
Bacillus subtilis cells grown in yeast extract medium accumulated 3-fluoro-l-erythro-[1,2-(14)C(2)]malate more than 30-fold from the surrounding medium. No metabolic products derived from 3-fluoro-l-erythro-malate could be detected in these cells. l-Malate competitively inhibited transport of 3-fluoro-l-erythro-malate. This malate analogue was itself a competitive inhibitor of l-malate uptake. Cells that had been grown in yeast extract supplemented with 5 mM l-malate showed a 10-fold increased… CONTINUE READING