C3d and the septal microvasculature as a predictor of chronic lung allograft dysfunction.

@article{Magro2006C3dAT,
  title={C3d and the septal microvasculature as a predictor of chronic lung allograft dysfunction.},
  author={Cynthia M. Magro and Abbas El-Sayed Abbas and Kay H Seilstad and Amy L. Pope-Harman and Tibor Nadasdy and Patrick Ross},
  journal={Human immunology},
  year={2006},
  volume={67 4-5},
  pages={274-83}
}
Studies have shown a potential role for humoral rejection in the evolution of lung graft dysfunction, apparently based on antibodies without human leukocyte antigen specificity. The correlation between extent of C4d deposition with clinical status further illustrates the importance of humoral immunity. Our study examines the potential value of C3d as a further diagnostic adjunct. C3d deposition was examined in lung allograft specimens using frozen tissue indirect direct immunofluorescence (IIF… CONTINUE READING