C3bi-binding protein on Candida albicans: temperature-dependent expression and relationship to human complement receptor type 3.

@article{Eigentler1989C3bibindingPO,
  title={C3bi-binding protein on Candida albicans: temperature-dependent expression and relationship to human complement receptor type 3.},
  author={A Eigentler and T F Schulz and C. Larcher and E M Breitwieser and Barry L. Myones and Andreas L. Petzer and Manfred Paul Dierich},
  journal={Infection and immunity},
  year={1989},
  volume={57 2},
  pages={
          616-22
        }
}
We investigated in detail the previously described capacity of pseudohyphae of Candida albicans to bind C3-coated particles. We show that the expression of the C3bi receptor of C. albicans was dependent upon the growth temperature of the fungi. C. albicans grown at 30 degrees C bound strongly to EAC1423bi, whereas those cells grown at 38.5 degrees C were completely devoid of this capacity. The molecule responsible for the attachment of EAC1423bi was heat labile and trypsin sensitive. Several… CONTINUE READING

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Complement in Candida albicans infections.

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  • 2009
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