C3 nephritic factor associated with C3 glomerulopathy in children

@article{Nicolas2013C3NF,
  title={C3 nephritic factor associated with C3 glomerulopathy in children},
  author={Camille Nicolas and Vincent Vuiblet and V{\'e}ronique Baudouin and M S Macher and Isabele Vrillon and Nathalie Biebuyck-Goug{\'e} and Maud Dehennault and Sophie Gi{\'e} and Denis Morin and Hubert Nivet and François Nobili and Tim Ulinski and Bruno Ranchin and Maria Chiarra Marinozzi and St{\'e}phanie Ngo and V{\'e}ronique Fr{\'e}meaux-Bacchi and Christine Pi{\`e}trement},
  journal={Pediatric Nephrology},
  year={2013},
  volume={29},
  pages={85-94}
}
C3 glomerulopathy (C3G) is characterized by predominant C3 deposits in glomeruli and dysregulation of the alternative pathway of complement. Half of C3G patients have a C3 nephritic factor (C3NeF). C3G incorporated entities with a range of features on microscopy including dense deposit diseases (DDD) and C3 glomerulonephritis (C3GN). The aim of this work was to study children cases of C3G associated with C3NeF. We reviewed 18 cases of C3G with a childhood onset associated with C3NeF without… CONTINUE READING
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