C282Y-HFE Gene Variant Affects Cholesterol Metabolism in Human Neuroblastoma Cells

Abstract

Although disruptions in the maintenance of iron and cholesterol metabolism have been implicated in several cancers, the association between variants in the HFE gene that is associated with cellular iron uptake and cholesterol metabolism has not been studied. The C282Y-HFE variant is a risk factor for different cancers, is known to affect sphingolipid… (More)
DOI: 10.1371/journal.pone.0088724

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@inproceedings{AliRahmani2014C282YHFEGV, title={C282Y-HFE Gene Variant Affects Cholesterol Metabolism in Human Neuroblastoma Cells}, author={Fatima Ali-Rahmani and Michael A. Huang and C Schengrund and James R. Connor and Sang Y Lee}, booktitle={PloS one}, year={2014} }