C1q enhances the phagocytosis of Cryptococcus neoformans blastospores by human monocytes.

Abstract

We investigated whether C1q, a subunit of the first component of C, could modulate human peripheral blood monocyte-mediated phagocytosis of Cryptococcus neoformans (CN). Adherence of monocytes to C1q-coated surfaces induced a significant enhancement of ingestion of CN blastospores that had been opsonized with specific anticapsular IgG (IgG-CN). Additionally… (More)

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Cite this paper

@article{Bobak1988C1qET, title={C1q enhances the phagocytosis of Cryptococcus neoformans blastospores by human monocytes.}, author={David A. Bobak and Ronald G. Washburn and M M Frank}, journal={Journal of immunology}, year={1988}, volume={141 2}, pages={592-7} }