C1q: the perfect complement for a synaptic feast?

@article{Perry2008C1qTP,
  title={C1q: the perfect complement for a synaptic feast?},
  author={V Hugh Perry and V M O'connor},
  journal={Nature Reviews Neuroscience},
  year={2008},
  volume={9},
  pages={807-811}
}
The efficient and selective removal of apoptotic cells is an important feature of tissue development, homeostasis and pathology. In the nervous system, synapses and distal axons are selectively eliminated as part of the remodelling that underpins development and pathology, through a process that has some features in common with apoptotic cell removal. Components of the complement cascade are implicated in the efficient removal of apoptotic cells outside the nervous system, and recent evidence… CONTINUE READING
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