C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition.

@article{Rueda2005C1858TFV,
  title={C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition.},
  author={B. Bryan Rueda and Concepci{\'o}n N{\'u}{\~n}ez and Gisela Orozco and Miguel {\'A}ngel L{\'o}pez-Nevot and Emilio G{\'o}mez de la Concha and Javier Mart{\'i}n and Elena Urcelay},
  journal={Human immunology},
  year={2005},
  volume={66 7},
  pages={848-52}
}
Recent findings have demonstrated that the single nucleotide polymorphism 1858C-->T located at the P1 motif of the PTPN22 (protein tyrosine phosphatase nonreceptor 22) gene has functional relevance and is associated with a variety of autoimmune diseases. The aim of this study was to assess the role of the PTPN22 1858C-->T polymorphism in the genetic predisposition to celiac disease (CD). We analyzed a case-control cohort composed by 534 patients with CD and 653 healthy controls and additionally… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…