C1473G polymorphism in mouse tryptophan hydroxylase-2 gene in the regulation of the reaction to emotional stress.

Abstract

Neurotransmitter serotonin (5-HT) is involved in the regulation of stress response. Tryptophan hydroxylase-2 (TPH2) is the key enzyme of serotonin (5-HT) synthesis in the brain. C1473G polymorphism in Tph2 gene is the main factor defining the enzyme activity in the brain of laboratory mice. The effect of interaction between C1473G polymorphism and 30min… (More)
DOI: 10.1016/j.neulet.2017.01.010

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@article{Bazhenova2017C1473GPI, title={C1473G polymorphism in mouse tryptophan hydroxylase-2 gene in the regulation of the reaction to emotional stress.}, author={Ekaterina Yu Bazhenova and Daria V Bazovkina and Elizabeth A. Kulikova and Dariya V Fursenko and Nikita V Khotskin and Daria V. Lichman and Alexander V. Kulikov}, journal={Neuroscience letters}, year={2017}, volume={640}, pages={105-110} }