C. elegans sperm bud vesicles to deliver a meiotic maturation signal to distant oocytes.

@article{Kosinski2005CES,
  title={C. elegans sperm bud vesicles to deliver a meiotic maturation signal to distant oocytes.},
  author={Mary E Kosinski and Kent Mcdonald and Joel C. Schwartz and Ikuko Yamamoto and David Greenstein},
  journal={Development},
  year={2005},
  volume={132 15},
  pages={3357-69}
}
The major sperm protein (MSP) is the central cytoskeletal element required for actin-independent motility of nematode spermatozoa. MSP has a dual role in Caenorhabditis elegans reproduction, functioning as a hormone for both oocyte meiotic maturation and ovarian muscle contraction. The identification of the signaling function of MSP raised the question, how do spermatozoa, which are devoid of ribosomes, ER and Golgi, release a cytoplasmic protein lacking a signal sequence? Here, we provide… CONTINUE READING

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