C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.

@article{ORourke2009CEM,
  title={C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.},
  author={Eyleen J. O'Rourke and Alexander A. Soukas and Christopher E. Carr and Gary Ruvkun},
  journal={Cell metabolism},
  year={2009},
  volume={10 5},
  pages={430-5}
}
Genetic conservation allows ancient features of fat storage endocrine pathways to be explored in C. elegans. Multiple studies have used Nile red or BODIPY-labeled fatty acids to identify regulators of fat mass. When mixed with their food, E. coli bacteria, Nile red, and BODIPY-labeled fatty acids stain multiple spherical cellular structures in the C. elegans major fat storage organ, the intestine. However, here we demonstrate that, in the conditions previously reported, the lysosome-related… CONTINUE READING
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