• DOI:10.1016/S0896-6273(00)81199-X
Corpus ID: 9247380

C. elegans Locomotory Rate Is Modulated by the Environment through a Dopaminergic Pathway and by Experience through a Serotonergic Pathway

@article{Sawin2000CEL,
  title={C. elegans Locomotory Rate Is Modulated by the Environment through a Dopaminergic Pathway and by Experience through a Serotonergic Pathway},
  author={E. R. Sawin and R. Ranganathan and H. Horvitz},
  journal={Neuron},
  year={2000},
  volume={26},
  pages={619-631}
}

E. R. Sawin, R. Ranganathan, H. Horvitz

Published 2000

Biology, Medicine

Neuron

Caenorhabditis elegans modulates its locomotory rate in response to its food, bacteria, in two ways. First, well-fed wild-type animals move more slowly in the presence of bacteria than in the absence of bacteria. This basal slowing response is mediated by a dopamine-containing neural circuit that senses a mechanical attribute of bacteria and may be an adaptive mechanism that increases the amount of time animals spend in the presence of food. Second, food-deprived wild-type animals, when… CONTINUE READING

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