C. elegans ATAD-3 Is Essential for Mitochondrial Activity and Development

@inproceedings{Hoffmann2009CEA,
  title={C. elegans ATAD-3 Is Essential for Mitochondrial Activity and Development},
  author={Michael Hoffmann and Nad{\'e}ge Bellance and Rodrigue Rossignol and Werner J. H. Koopman and Peter H G M Willems and Ertan Mayatepek and Olaf Bossinger and Felix Distelmaier},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND Mammalian ATAD3 is a mitochondrial protein, which is thought to play an important role in nucleoid organization. However, its exact function is still unresolved. RESULTS Here, we characterize the Caenorhabditis elegans (C. elegans) ATAD3 homologue (ATAD-3) and investigate its importance for mitochondrial function and development. We show that ATAD-3 is highly conserved among different species and RNA mediated interference against atad-3 causes severe defects, characterized by early… CONTINUE READING

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  • Journal of Bioenergetics and Biomembranes
  • 2012
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References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

Mitochondria in health and disease: perspectives on a new mitochondrial biology.

  • Molecular aspects of medicine
  • 2004
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL