C-type natriuretic peptide receptor expression in pancreatic alpha cells

  title={C-type natriuretic peptide receptor expression in pancreatic alpha cells},
  author={Matthew D. Burgess and Kim D. Moore and Gay M. Carter and Abdel A Alli and Christopher S. Granda and Hirohito Ichii and Camillo Ricordi and William Gower},
  journal={Histochemistry and Cell Biology},
Atrial natriuretic peptide (ANP), brain type natriuretic peptide (BNP) and C-type natriuretic peptide (CNP) comprise a family of natriuretic peptides that mediate their biological effects through three natriuretic peptide receptor subtypes, NPR-A (ANP, BNP), NPR-B (CNP) and NPR-C (ANP, BNP, CNP). Several reports have provided evidence for the expression of ANP and specific binding sites for ANP in the pancreas. The purpose of this study was to identify the ANP receptor subtype and to localize… CONTINUE READING


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