C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain.

@article{Sudoh1990CtypeNP,
  title={C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain.},
  author={Tetsuji Sudoh and Naoto Minamino and Kenji Kangawa and Hisayuki Matsuo},
  journal={Biochemical and biophysical research communications},
  year={1990},
  volume={168 2},
  pages={
          863-70
        }
}
Isolation and identification of C-type natriuretic peptide in chicken brain.
N-terminally extended form of C-type natriuretic peptide (CNP-53) identified in porcine brain.
Cellular and Molecular Aspects of C-Type Natriuretic Peptide (CNP)
TLDR
It is demonstrated that the major molecular forms in the human brain are C NP-22 and CNP-53, which are identical in pig, rat, human, and mouse precursors.
Gene and precursor structure of porcine C-type natriuretic peptide.
Isolation and sequence determination of frog C-type natriuretic peptide.
Natriuretic peptides and therapeutic applications
TLDR
The NP system thus serves as an important compensatory mechanism against neurohumoral activation in heart failure and provides a strong rationale for the use of exogenous NPs in the management of acutely decompensated heart failure.
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References

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A new natriuretic peptide in porcine brain
Atrial natriuretic peptide (ANP), a hormone secreted from mammalian atria, regulates the homoeostatic balance of body fluid and blood pressure1–3. ANP-like immunoreactivity is also present in the
Identification of new atrial natriuretic peptides in frog heart.
Identification of a 29-amino acid natriuretic peptide in chicken heart.
Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases
TLDR
The cloning and expression of a second human natriuretic peptide-receptor guanylate cyclase, the ANP-B receptor, is reported, which is preferentially activated by porcine brain natriuric peptide rather than human α-ANP, and may have important implications for the understanding of the central and peripheral control of cardiovascular homeostasis.
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